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评估天然物质中潜在生物活性的体外试验。

In vitro tests to evaluate potential biological activity in natural substances.

作者信息

Nano G M, Binello A, Bianco M A, Ugazio G, Burdino S

机构信息

Dipartimento di Scienza e Tecnologia del Farmaco, Universita' di Torino, Via Pietro Giuria, 9 10125, Torino, Italy.

出版信息

Fitoterapia. 2002 Apr;73(2):140-6. doi: 10.1016/s0367-326x(02)00014-x.

Abstract

The biological activity of polysaccharides from the mycelia of 40 Basidiomycetes was studied using an uncommon toxicity test technique, the planaria bioassay, and the better known potato disk bioassay. The results showed the utility of this duo of 'in vitro' tests as a preliminary screening of the toxicity of substances that are present in aqueous fungal extracts.

摘要

利用一种不常见的毒性测试技术——涡虫生物测定法以及更为人熟知的马铃薯圆片生物测定法,对40种担子菌菌丝体中的多糖的生物活性进行了研究。结果表明,这两种“体外”测试方法可用于初步筛选真菌水提取物中存在的物质的毒性。

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