Katzen J T, McCarthy J G
Institute of Reconstructive Plastic Surgery, Variety Center for Craniofacial Rehabilitation, New York University Medical Center, New York, New York, USA.
Otolaryngol Clin North Am. 2000 Dec;33(6):1257-84, vi. doi: 10.1016/s0030-6665(05)70280-2.
This article reviews a number of well-known syndromes involving craniofacial synostosis and associated midface deficiencies. Syndromes discussed include Apert's, Crouzon's, Saethre-Chotzen, and Carpenter's. Clinical characteristics and genetic defects are discussed. A general approach to surgical management is outlined.
本文综述了一些涉及颅面骨缝早闭及相关面中部发育不全的著名综合征。所讨论的综合征包括阿佩尔氏综合征、克鲁宗氏综合征、塞特勒-肖滕氏综合征和卡彭特氏综合征。文中讨论了其临床特征和基因缺陷。概述了手术治疗的一般方法。
