Bershteĭn L M, Tsyrlina E V, Poroshina T E, Bychkova N V, Kalinina N M, Gamaiunova V B, Kriuchkova O G, Kovalenko I G, Vasil'ev D A
Petrov Research Institute of Oncology, 189646, St. Petersburg, Pesochny-2, Russia.
Ross Fiziol Zh Im I M Sechenova. 2001 Apr;87(4):525-31.
Drinking of 5% ethanol in combination with estradiol induced genotoxic (G) changes in the rat uterine tissue. The changes could be prevented by N-acetylcysteine or melatonin. The data obtained suggest that ascorbic acid and alpha-tocopherol may be recommended in combination with N-acetylcysteine for repair of estrogen effect switching phenomenon.
饮用5%乙醇与雌二醇的组合会在大鼠子宫组织中诱导遗传毒性(G)变化。这些变化可被N-乙酰半胱氨酸或褪黑素预防。所获得的数据表明,抗坏血酸和α-生育酚可与N-乙酰半胱氨酸联合推荐用于修复雌激素效应转换现象。