Adani G L, Marcello D, Anania G, Mazzetti J, Jorizzo E F, Maestroni U, Donini A
Dipartimento di Scienze Chirurgiche, Radiologiche e Anestesiologiche Sezione di Clinica Chirurgica Università degli Studi di Ferrara.
Chir Ital. 2001 May-Jun;53(3):405-7.
The occurrence of cutaneous metastasis from colorectal cancer is rare, with a reported frequency of less than 4 to 5 percent. Typically signifies widespread disease and a poor prognosis. Metastases from adenocarcinoma of the colon-rectum usually occur within two years of resection of the primary tumour, and the average survival of a patient with cutaneous metastasis has been reported as ranging from 3 to 18 months. The case reported here concerns a patient who developed a skin metastasis without evidence of visceral involvement after treatment of rectal carcinoma. It is advisable to implement cutaneous biopsy in patients with a history of carcinoma; this may establish the diagnosis of metastatic disease and change the methods of therapeutic intervention and prognosis.
结直肠癌皮肤转移的发生率很低,报告的频率不到4%至5%。这通常意味着疾病广泛扩散且预后不良。结肠直肠癌腺癌转移通常发生在原发肿瘤切除后的两年内,据报道,皮肤转移患者的平均生存期为3至18个月。本文报告的病例是一名直肠癌患者在治疗后出现皮肤转移但无内脏受累证据。对于有癌症病史的患者,建议进行皮肤活检;这可能有助于确诊转移性疾病,并改变治疗干预方法和预后。