离子稳态与细胞凋亡。
Ion homeostasis and apoptosis.
作者信息
Yu S P, Canzoniero L M, Choi D W
机构信息
Center for the Study of Nervous System Injury and Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Missouri 63110, St. Louis, USA.
出版信息
Curr Opin Cell Biol. 2001 Aug;13(4):405-11. doi: 10.1016/s0955-0674(00)00228-3.
Abstract
Alterations in the transmembrane gradients of several physiological ions may influence programmed cell death. In particular, recent data suggest that increases in intracellular calcium may either promote or inhibit apoptosis, depending on the level, timing and location, whereas loss of intracellular potassium promotes apoptosis.
摘要
几种生理离子跨膜梯度的改变可能影响程序性细胞死亡。特别是，最近的数据表明，细胞内钙的增加可能促进或抑制细胞凋亡，这取决于其水平、时间和位置，而细胞内钾的流失则促进细胞凋亡。
Zotero 插件