Graham J, Lin C S, Kaas J H
J Comp Neurol. 1979 Oct 1;187(3):557-80. doi: 10.1002/cne.901870307.
Subcortical projections of six visual cortical areas (Areas 17 and 18, the Middle Temporal, Dorsomedial and Medial Areas, and the Posterior Parietal Region) in the owl monkey, Aotus trivigatus, were investigated with autoradiographic methods following injections of tritiated proline. No contralateral projections were demonstrated. While some brainstem structures received input from all six subdivisions of cortex, each cortical area appeared to exhibit its own unique pattern of subcortical projections. All six cortical areas were found to project to the superior and inferior divisions of the pulvinar, reticular nucleus of the thalamus, pretectum and superior colliculus. Other subcortical targets of one or more visual cortical areas were the basal ganglia, claustrum, zona incerta, one or more of the intralaminar nuclei, lateral posterior nucleus, pregeniculate nucleus, dorsal lateral geniculate nucleus, and pontine nuclei. Furthermore, details of corticofugal projections to the dorsal lateral geniculate nucleus, pretectum and superior colliculus varied with the cortical area studied. The projections to the reticular nucleus, pregeniculate nucleus, dorsal lateral geniculate nucleus, the inferior and a portion of the superior division of the pulvinar and the superior colliculus were found to be topographically organized. The targets of the subcortical projections were compared with those of the retina, as revealed by autoradiographic methods following tritiated proline injections of the eye and were found to overlap to varying extents in the superior colliculus, pretectum and dorsal lateral geniculate nucleus and to be segregated in the pregeniculate nucleus. The results substantiate the validity of previous studies in the owl monkey that suggest that the visual cortex is subdivided into several functionally distinct areas; and illustrate the complexity of corticofugal influence on visual processing.
采用放射自显影法，在注入氚化脯氨酸后，对夜猴（Aotus trivigatus）六个视觉皮层区域（17区和18区、颞中区、背内侧区和内侧区以及顶叶后区）的皮层下投射进行了研究。未发现对侧投射。虽然一些脑干结构接受来自皮层所有六个亚区的输入，但每个皮层区域似乎都表现出其独特的皮层下投射模式。发现所有六个皮层区域都投射到丘脑枕的上、下部分、丘脑网状核、顶盖前区和上丘。一个或多个视觉皮层区域的其他皮层下靶点包括基底神经节、屏状核、未定带、一个或多个板内核、外侧后核、膝前核、背外侧膝状核和脑桥核。此外，投射到背外侧膝状核、顶盖前区和上丘的皮质传出投射细节因所研究的皮层区域而异。发现投射到网状核、膝前核、背外侧膝状核、丘脑枕下部分和上部分的一部分以及上丘的投射是按拓扑方式组织的。通过对眼睛注入氚化脯氨酸后的放射自显影法揭示，将皮层下投射的靶点与视网膜的靶点进行了比较，发现它们在上丘、顶盖前区和背外侧膝状核中不同程度地重叠，而在膝前核中是分开的。这些结果证实了夜猴先前研究的有效性，这些研究表明视觉皮层被细分为几个功能不同的区域；并说明了皮质传出对视觉处理影响的复杂性。
