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溴隐亭使两例高泌乳素血症性下丘脑闭经患者妊娠。

Bromocriptine induced pregnancy in two cases of euprolactinemic hypothalamic amenorrhea.

作者信息

Nencioni T, Miragoli A, Dorato F, Polvani F

出版信息

J Endocrinol Invest. 1978 Jan;1(1):65-7. doi: 10.1007/BF03346772.

Abstract

Two euprolactinemic women with hypothalamic amenorrhea, previously unsuccessfully submitted to clomiphene citrate therapy, were treated with bromocriptine. PRL secretion was studied in basal conditions and under dynamic tests: TRH and chlorpromazine. Serum FSH, LH and 17-beta-estradiol were determined before and during the treatment. Both patients conceived, and one delivered a healthy baby at term. Bromocriptine appears to be an effective drug for treating women with hypothalamic amenorrhea, particularly those unresponsive to clomiphene.

摘要

两名患有下丘脑性闭经的高泌乳素血症女性,此前接受克罗米芬枸橼酸盐治疗未成功,接受了溴隐亭治疗。在基础条件下以及动态试验(促甲状腺激素释放激素和氯丙嗪)中研究了泌乳素(PRL)分泌情况。在治疗前和治疗期间测定了血清促卵泡生成素(FSH)、促黄体生成素(LH)和17-β-雌二醇。两名患者均受孕,其中一名足月产下一名健康婴儿。溴隐亭似乎是治疗下丘脑性闭经女性的有效药物,尤其是那些对克罗米芬无反应的患者。

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