Le Roith D, Potashnik G, Glick S M
Int J Fertil. 1979;24(2):145-7.
The effect of bromocriptine was studied in a 28-year-old cretin woman who presented with long-term untreated primary hypothyroidism, primary amenorrhea, hyperprolactinemia, and an enlarged pituitary fossa. Bromocriptine therapy lowered the plasma prolactin and caused an early rise in plasma 17 beta-estradiol levels and uterine bleeding, despite the failure of plasma gonadotrophins to respond to luteinizing hormone release hormone (LHRH) administration. Thus, it is suggested that bromocriptine may have an early direct effect on the ovary in hyperprolactinemic amenorrhea.
对一名28岁的克汀病女性进行了溴隐亭疗效研究，该患者患有长期未经治疗的原发性甲状腺功能减退、原发性闭经、高泌乳素血症和垂体窝扩大。尽管血浆促性腺激素对注射促黄体生成素释放激素（LHRH）无反应，但溴隐亭治疗降低了血浆泌乳素水平，并使血浆17β-雌二醇水平早期升高及子宫出血。因此，提示溴隐亭可能对高泌乳素血症性闭经患者的卵巢有早期直接作用。
