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门诊根治性前列腺切除术:标准会阴入路对患者预后的影响。

Outpatient radical prostatectomy: impact of standard perineal approach on patient outcome.

作者信息

Ruiz-Deya G, Davis R, Srivastav S K, M Wise A, Thomas R

机构信息

Department of Urology, Health Sciences Center and Department of Biostatistics, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana.

出版信息

J Urol. 2001 Aug;166(2):581-6. doi: 10.1016/s0022-5347(05)65988-5.

Abstract

PURPOSE

As managed care becomes more prevalent, urologists must critically evaluate the economic aspect of and patient satisfaction with urological practice patterns. We have previously reported the advantages of radical perineal prostatectomy, which decreases hospitalization and morbidity, and provides a more rapid return to normal activity, translating into cost savings. We have since evaluated the satisfaction of patients who underwent outpatient radical prostatectomy with and without laparoscopic pelvic lymph node dissection.

MATERIALS AND METHODS

We evaluated the charts of 250 consecutive patients who underwent outpatient radical perineal prostatectomy with less than 24 hours of hospitalization from 1992 to 1997. Complications, pain management, blood transfusion, and bowel and urinary dysfunction were assessed. Validated quality of life questionnaires were mailed to 200 patients several months postoperatively and a 62% response rate was achieved.

RESULTS

Mean followup in the series was 30 months. In the perioperative period there were rectal perforation in less than 2% of patients, anastomotic stricture in 3%, perineal fistula in 0.4% and blood transfusion in 11%. Some problems with bowel movements immediately after the procedure, such as diarrhea, constipation or soiled underwear, developed in 17% of patients, of whom up to 20% had had some bowel dysfunction before surgery. In the majority bowel problems resolved in an average of 7.3 weeks. Persistent new onset bowel trouble developed in 9 of the 124 patients (7%). The questionnaire demonstrated persistent significant urinary incontinence in 8 cases (7%). Nerve sparing was attempted in 54 patients, including 22 (41%) who achieve erection sufficient for vaginal penetration and are satisfied with sexual function. Of the patients 17% reported problems after hospital discharge that were mostly related to Foley catheter management. Overall 94.8% of patients were satisfied with treatment. Physical and social/family well-being appeared to be excellent according to the questionnaire. Only 12% of patients would have preferred longer hospitalization. The preferred method of pain control was nonsteroidal anti-inflammatory drugs.

CONCLUSIONS

Radical perineal prostatectomy is a low morbidity alternative for localized prostate cancer. Outpatient radical perineal prostatectomy may be performed with good patient satisfaction and safety. There appear to be few bowel problems after long-term followup.

摘要

目的

随着管理式医疗日益普及,泌尿外科医生必须严格评估泌尿外科诊疗模式的经济层面以及患者满意度。我们之前报道了根治性会阴前列腺切除术的优势,该手术可减少住院时间和发病率,并能使患者更快恢复正常活动,从而节省成本。此后,我们评估了接受或未接受腹腔镜盆腔淋巴结清扫术的门诊根治性前列腺切除术患者的满意度。

材料与方法

我们评估了1992年至1997年间连续250例行门诊根治性会阴前列腺切除术且住院时间少于24小时的患者的病历。评估了并发症、疼痛管理、输血情况以及肠道和排尿功能障碍。在术后数月向200例患者邮寄了经过验证的生活质量问卷,回复率为62%。

结果

该系列患者的平均随访时间为30个月。围手术期,不到2%的患者发生直肠穿孔,3%的患者出现吻合口狭窄,0.4%的患者发生会阴瘘,11%的患者需要输血。17%的患者术后立即出现一些排便问题,如腹泻、便秘或弄脏内裤,其中高达20%的患者术前就存在一些肠道功能障碍。大多数肠道问题平均在7.3周内得到解决。124例患者中有9例(7%)出现持续的新发肠道问题。问卷显示8例(7%)患者存在持续的明显尿失禁。对54例患者尝试进行了神经保留,其中22例(41%)实现了足以进行阴道插入的勃起并对性功能满意。17%的患者报告出院后存在问题,主要与导尿管管理有关。总体而言,94.8%的患者对治疗满意。根据问卷,患者的身体和社会/家庭幸福感似乎极佳。只有12%的患者希望住院时间更长。首选的疼痛控制方法是非甾体类抗炎药。

结论

根治性会阴前列腺切除术是局限性前列腺癌发病率较低的一种治疗选择。门诊根治性会阴前列腺切除术可在患者满意度高且安全的情况下进行。长期随访后似乎很少有肠道问题。

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