Parati G, Di Rienzo M, Mancia G
Istituto Scientifico Ospedale San Luca, Istituto Auxologico Italiano, via Spagnoletto, 3 20149 Milano, Italy.
Ann N Y Acad Sci. 2001 Jun;940:469-87. doi: 10.1111/j.1749-6632.2001.tb03699.x.
Assessment of arterial baroreflex function in humans through laboratory tests has provided a great deal of information of pathophysiological and clinical relevance. Indeed, the sensitivity of the baroreceptor-heart rate reflex quantified through these laboratory methods was shown to predict the risk of cardiovascular events and death from myocardial infarction, heart failure, and in diabetic patients. This traditional approach, however, does not provide information on daily life baroreflex cardiovascular control. Modern techniques, based on computer analysis of spontaneous blood pressure and heart rate fluctuations, are now available and allow baroreflex sensitivity to be assessed under real-life conditions with no need for external stimulation. In particular, these methods offer the possibility of investigating the dynamic modulation of baroreflex sensitivity occurring either on a minute-to-minute basis or over 24 hours.
通过实验室测试评估人类的动脉压力反射功能，已经提供了大量具有病理生理学和临床相关性的信息。事实上，通过这些实验室方法量化的压力感受器 - 心率反射敏感性，已被证明可以预测心血管事件以及心肌梗死、心力衰竭和糖尿病患者死亡的风险。然而，这种传统方法无法提供日常生活中压力反射对心血管控制的信息。基于对自发性血压和心率波动进行计算机分析的现代技术现已问世，无需外部刺激就能在现实生活条件下评估压力反射敏感性。特别是，这些方法提供了研究压力反射敏感性在每分钟或24小时内动态调节的可能性。
