Mancia G, Grassi G
Cattedra di Medicina Interna, Ospedale S. Gerardo, Monza, Italy.
Clin Exp Hypertens. 1995 Jan-Feb;17(1-2):387-97. doi: 10.3109/10641969509087079.
In recent years assessment of baroreflex cardiovascular control in humans has received growing attention for two major reasons, i.e. 1) the availability of new techniques to evaluate this reflex function and 2) the possibility that a baroreflex alteration might play a role in the clinical evolution of cardiovascular diseases. This paper will briefly examine the alterations in baroreflex function in a variety of diseases affecting the circulation. In particular it will be focused on 1) the baroreflex control of heart rate and microneurographically measured muscle sympathetic nerve traffic in human hypertension, 2) the impairment of this reflex homeostatic function occurring in congestive heart failure of different clinical severity and finally 3) the transient alterations in baroreflex-heart rate control occurring in man in the acute post-myocardial infarction phase and during episodes of spontaneous myocardial ischemia.
近年来，人体压力反射心血管控制的评估受到越来越多的关注，主要有两个原因，即：1）出现了评估这种反射功能的新技术；2）压力反射改变可能在心血管疾病的临床进展中起作用。本文将简要探讨影响循环系统的各种疾病中压力反射功能的改变。特别关注以下几点：1）人类高血压中压力反射对心率的控制以及通过微神经ography测量的肌肉交感神经活动；2）不同临床严重程度的充血性心力衰竭中这种反射稳态功能的损害；最后3）急性心肌梗死后阶段及自发性心肌缺血发作期间人体压力反射-心率控制的短暂改变。
