Clark K F, Farber J P
Department of Otorhinolaryngology, University of Oklahoma Health Sciences Center, Oklahoma City 73190, USA.
Ann Otol Rhinol Laryngol Suppl. 2001 Jul;187:18-31. doi: 10.1177/00034894011100s702.
We tested the hypothesis that vocal fold paresis leads to a substantial reduction in activity from the internal branch of the superior laryngeal nerve (iSLN) during respiration and evoked vocalization. The iSLN afferent activity was measured before and after recurrent laryngeal nerve paresis by cold block in decerebrate cats during spontaneous respiration and electrically evoked vocalization. Response rate patterns of 33 iSLN single units from 11 cats were categorized into 5 groups based on responses to vocalization. Only 24% of single units during spontaneous respiration and 18% during evoked phonation displayed activity pattern changes as a result of paresis. Those fibers affected were heterogeneous in discharge pattern, but none of the units that followed voice frequency lost this characteristic when the motor nerve was cooled. The relative insensitivity of iSLN activity to motor paralysis suggests that the receptors studied are coupled to tissue such that passive interaction rather than active muscular contraction is the major stimulus.
在呼吸和诱发发声过程中，声带麻痹会导致喉上神经内支（iSLN）的活动大幅减少。通过对去大脑猫进行冷阻滞，在自发呼吸和电诱发发声期间，测量了喉返神经麻痹前后iSLN的传入活动。根据对发声的反应，将11只猫的33个iSLN单个单位的反应率模式分为5组。在自发呼吸期间，只有24%的单个单位以及在诱发发声期间18%的单个单位由于麻痹而出现活动模式变化。那些受影响的纤维在放电模式上是异质性的，但当运动神经冷却时，没有一个跟随语音频率的单位失去这一特征。iSLN活动对运动麻痹的相对不敏感性表明，所研究的感受器与组织相连，使得被动相互作用而非主动肌肉收缩是主要刺激因素。
