Clark K F, Farber J P
Department of Otorhinolaryngology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Ann Otol Rhinol Laryngol. 1998 Sep;107(9 Pt 1):753-60. doi: 10.1177/000348949810700903.
The goal of this study was to determine whether sensory fibers in an intact recurrent laryngeal nerve (RLN) are influenced by respiration or vocalization. Patterns of RLN afferent activity were examined during respiration and evoked vocalization by means of midbrain electrical stimulation in cats anesthetized with alpha-chloralose. Nerve bundles were dissected from an intact RLN, with motor function preserved. The bundles were cut and the laryngeal end was placed on floating bipolar electrodes. Fifteen right RLNs were examined. A total of 9 single and multiunit afferent fibers from 4 cats were isolated and examined during respiration. Four units, analyzed from 3 fibers, showed respiratory phase modulation. Eight units, analyzed from 4 fibers in 1 cat, were observed during vocalization and showed no vocalization phase modulation. The RLN afferents could contribute to reflex modulation of the respiratory cycle, but more extensive sampling would be necessary to preclude effects from vocalization.
本研究的目的是确定完整的喉返神经（RLN）中的感觉纤维是否受呼吸或发声的影响。通过对用α-氯醛糖麻醉的猫进行中脑电刺激，在呼吸和诱发发声期间检查RLN传入活动的模式。从完整的RLN中解剖出神经束，同时保留其运动功能。将神经束切断，将喉部末端置于浮动双极电极上。检查了15条右侧RLN。在呼吸期间，从4只猫中总共分离并检查了9条单根和多根传入纤维。从3条纤维中分析出的4个单位显示出呼吸相位调制。在发声期间观察到从1只猫的4条纤维中分析出的8个单位，且未显示出发声相位调制。RLN传入纤维可能有助于呼吸周期的反射调节，但需要更广泛的采样以排除发声的影响。
