Guilleminault C, Brooks S N
Stanford Sleep Disorders Clinic, Stanford Hospital and Clinics, Stanford University and Medical Centre, Stanford, California 94305, USA.
Brain. 2001 Aug;124(Pt 8):1482-91. doi: 10.1093/brain/124.8.1482.
The complaint of excessive daytime sleepiness, commonly encountered in neurological practice, may arise from a variety of disorders. The list of possibilities spans virtually every major area of medicine, neurology and psychiatry. A clear, detailed history is invaluable in negotiating these numerous diagnostic considerations; however, the symptom may be expressed in terms that do not directly denote somnolence (e.g. 'tiredness' or 'fatigue'). Accurate diagnosis is important, not only because of the negative impacts of sleepiness and its root causes on health and social function, but because excessive sleepiness is generally remediable with appropriate treatment. As our understanding of the neurological underpinnings of alertness and sleepiness deepens, improved treatment methods are bound to emerge.
日间过度嗜睡这一主诉在神经科临床实践中很常见,可能由多种疾病引起。可能的病因几乎涵盖医学、神经学和精神病学的各个主要领域。一份清晰、详细的病史对于梳理这些众多的诊断考量因素非常宝贵;然而,该症状可能以并非直接表示嗜睡的表述出现(例如“疲倦”或“乏力”)。准确诊断很重要,这不仅是因为嗜睡及其根源对健康和社会功能有负面影响,还因为通过适当治疗,过度嗜睡通常是可治愈的。随着我们对警觉和嗜睡的神经学基础的理解不断深入,必然会出现更好的治疗方法。