Muffoletto A J, Ketonen L M, Mader J T, Crow W N, Hadjipavlou A G
Department of Orthopaedics and Rehabilitation, University of Texas Medical Branch, Galveston, Texas 77555-0792, USA.
Spine (Phila Pa 1976). 2001 Jul 15;26(14):1570-6. doi: 10.1097/00007632-200107150-00014.
Retrospective.
To determine the incidence, clinical presentation, diagnostic laboratory values, imaging characteristics, and optimal treatment of hematogenous pyogenic facet joint infections.
There are 27 documented cases of hematogenous pyogenic facet joint infections. Data regarding incidence, clinical presentation, diagnosis, and treatment response are incomplete because of the paucity of reported cases.
This is a retrospective study of all cases of hematogenous pyogenic facet joint infection treated at one institution. Data from previous publications were combined with the present series to identify pertinent clinical characteristics and response to treatment.
A total of six cases (4%) of hematogenous pyogenic facet joint infection were identified of 140 cases of hematogenous pyogenic spinal infection at our institution. Combining all reported cases reveals the following: The average patient age is 55 years. Ninety-seven percent of cases occur in the lumbar spine. Epidural abscess formation complicates 25% of the cases of which 38% develop severe neurologic deficit. Erythrocyte sedimentation rate and C-reactive protein are elevated in all cases. Staphylococcus aureus is the most common infecting organism. Magnetic resonance imaging is accurate in identifying the septic joint and associated abscess formation. Percutaneous drainage of the involved joint has a higher rate of success (85%) than treatment with antibiotics alone (71%), but the difference is not significant (P = 0.37).
Hematogenous pyogenic facet joint infection is a rare but underdiagnosed clinical entity. Facet joint infections may be complicated by abscess formation in the epidural space or in the paraspinal muscles. Uncomplicated cases treated with percutaneous drainage and antibiotics may fare better than those treated with antibiotics alone. Cases complicated by an epidural abscess and severe neurologic deficit should undergo immediate decompressive laminectomy.
回顾性研究。
确定血源性化脓性小关节感染的发病率、临床表现、诊断实验室值、影像学特征及最佳治疗方法。
有27例血源性化脓性小关节感染的记录病例。由于报告病例较少,关于发病率、临床表现、诊断和治疗反应的数据并不完整。
这是一项对某机构治疗的所有血源性化脓性小关节感染病例的回顾性研究。将既往发表的数据与本系列病例相结合,以确定相关的临床特征和治疗反应。
在本机构的140例血源性化脓性脊柱感染病例中,共确诊6例(4%)血源性化脓性小关节感染。综合所有报告病例显示如下情况:患者平均年龄为55岁。97%的病例发生在腰椎。25%的病例并发硬膜外脓肿形成,其中38%出现严重神经功能缺损。所有病例的红细胞沉降率和C反应蛋白均升高。金黄色葡萄球菌是最常见的感染病原体。磁共振成像在识别感染关节及相关脓肿形成方面准确无误。受累关节的经皮引流成功率(85%)高于单纯抗生素治疗(71%),但差异无统计学意义(P = 0.37)。
血源性化脓性小关节感染是一种罕见但诊断不足的临床病症。小关节感染可能并发硬膜外间隙或椎旁肌肉脓肿形成。经皮引流联合抗生素治疗的非复杂病例可能比单纯抗生素治疗的病例预后更好。并发硬膜外脓肿和严重神经功能缺损的病例应立即行减压性椎板切除术。