Motorina I, Crudden C M
Department of Chemistry, University of New Brunswick, P.O. Box 45222, Fredericton, New Brunswick E3B 6E2, Canada.
Org Lett. 2001 Jul 26;3(15):2325-8. doi: 10.1021/ol010096h.
[reaction: see text] A modified cinchona alkaloid was grafted onto a mesoporous molecular sieve and onto amorphous silica gel. These heterogeneous ligands were employed in the asymmetric dihydroxylation of olefins under Sharpless conditions. The supported ligands yielded equivalent enantioselectivity compared with that of the homogeneous system and were easily recovered and reused.
