Murphy B J
Department of Radiology, The University of Miami School of Medicine, The Joseph Applebaum MRI Center, FL 33136, USA.
Skeletal Radiol. 2001 Jun;30(6):305-11. doi: 10.1007/s002560100330.
To determine the accuracy of T2*-weighted three-dimensional (3D) gradient-echo articular cartilage imaging in the identification of grades 3 and 4 chondromalacia of the knee.
A retrospective evaluation of 80 patients who underwent both arthroscopic and MRI evaluation was performed. The 3D images were interpreted by one observer without knowledge of the surgical results. The medial and lateral femoral condyles, the medial and lateral tibial plateau, the patellar cartilage and trochlear groove were evaluated. MR cartilage images were considered positive if focal reduction of cartilage thickness was present (grade 3 chondromalacia) or if complete loss of cartilage was present (grade 4 chondromalacia). Comparison of the 3D MR results with the arthroscopic findings was performed.
Eighty patients were included in the study group. A total of 480 articular cartilage sites were evaluated with MRI and arthroscopy. Results of MR identification of grades 3 and 4 chondromalacia, all sites combined, were: sensitivity 83%, specificity 97%, false negative rate 17%, false positive rate 3%, positive predictive value 87%, negative predictive value 95%, overall accuracy 93%.
The results demonstrate that T2*-weighted 3D gradient-echo articular cartilage imaging can identify grades 3 and 4 chondromalacia of the knee.
确定T2*加权三维（3D）梯度回波关节软骨成像在识别膝关节3级和4级软骨软化症中的准确性。
对80例接受关节镜检查和MRI评估的患者进行回顾性评估。3D图像由一名不知道手术结果的观察者解读。评估了股骨内外侧髁、胫骨内外侧平台、髌软骨和滑车沟。如果存在软骨厚度局部减少（3级软骨软化症）或软骨完全缺失（4级软骨软化症），则MR软骨图像被视为阳性。将3D MR结果与关节镜检查结果进行比较。
80例患者纳入研究组。总共对480个关节软骨部位进行了MRI和关节镜检查评估。所有部位综合起来，MR识别3级和4级软骨软化症的结果为：灵敏度83%，特异性97%，假阴性率17%，假阳性率3%，阳性预测值87%，阴性预测值95%，总体准确率93%。
结果表明，T2*加权3D梯度回波关节软骨成像可识别膝关节3级和4级软骨软化症。
