Walter S, Basso A, Guiot G, Barrionuevo G, Gautron M
Adv Neurol. 1975;10:133-45.
Electrical stimulation of the ventrolateral (VL) nucleus of the thalamus was performed on hemicerebellectomized baboons. Stimulation was delivered in volleys of 40 to 60 Hz lasting 5 to 25 sec, and at intensities ranging from 1 to 6 mA (width of shock 0.5 to 5 msec). Similar parameters of stimulation produced asymmetrical motor and electrocortical responses. When the normal VL nucleus was stimulated, these responses were tonic or tonic-clonic. When the VL nucleus deprived of its cerebellar afferents was stimulated, the tonic-clonic responses were followed by afterdischarges appearing in the EEG which persisted after cessation of stimulation. The role of the cerebellum in the lowering of the excitability threshold of some structures, particularly the VL nucleus, is discussed, as are the systems likely to play a role in producing various clinical responses.
在半侧小脑切除的狒狒上对丘脑腹外侧（VL）核进行电刺激。刺激以40至60赫兹的阵发放送，持续5至25秒，强度范围为1至6毫安（电击宽度0.5至5毫秒）。类似的刺激参数产生不对称的运动和电皮质反应。当刺激正常的VL核时，这些反应是强直性或强直性阵挛性的。当刺激切断小脑传入纤维的VL核时，强直性阵挛反应之后脑电图中出现刺激停止后仍持续的后放电。讨论了小脑在降低某些结构（特别是VL核）的兴奋性阈值中的作用，以及可能在产生各种临床反应中起作用的系统。
