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Endoscopic evaluation of the gastrotolerance of short-term antalgic treatment with low dose k-diclofenac: a comparison of ibuprofen and aspirin.

作者信息

Mahé I, Mouly S, Mahé E, Diemer M, Knellwolf A L, Simoneau G, Caulin C, Bergmann J F

机构信息

Unité de Recherches Thérapeutiques, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France.

出版信息

Fundam Clin Pharmacol. 2001 Feb;15(1):61-3. doi: 10.1046/j.1472-8206.2001.00004.x.

Abstract

In a short-term gastro-duodenal endoscopic study in 12 healthy volunteers, the gastrotoxicity was not different after intake of diclofenac-K 12.5 mg (0.33) or ibuprofen 200 mg (0.42, P=0.66) but significantly higher after aspirin 500 mg (2.67, P=0.002).

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