Azma A, Tawfik O, Casparian J M
Departments of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA.
Breast J. 2001 May-Jun;7(3):195-8. doi: 10.1046/j.1524-4741.2001.007003195.x.
Poromas are sweat gland tumors classically reported to be of eccrine origin. However, it is now recognized that poromas may also be derived from apocrine glands. There are no prior reports of either type of poroma arising on the breast. We report the first case of a poroma of the breast. The lesion was localized to the areola of a 70-year-old woman and mimicked an underlying neoplasm of the breast. Because the histopathology demonstrated apparent continuity of a benign poroma with the infundibula of hair follicles, the diagnosis of apocrine poroma was made. The poroma in this case is of apocrine derivation. This report demonstrates that apocrine poromas should be considered in the clinical differential of acquired lesions on the areola, suggesting an underlying breast tumor. Apocrine poromas that are only partially biopsied may recur. Moreover, since apocrine poromas may potentially develop into apocrine porocarcinomas, analogous to eccrine poromas sometimes transforming into eccrine porocarcinomas, apocrine poromas should be completely excised.
汗孔瘤是经典报道为起源于小汗腺的汗腺肿瘤。然而，现在人们认识到汗孔瘤也可能起源于大汗腺。此前尚无关于乳房出现这两种类型汗孔瘤的报道。我们报告了首例乳房汗孔瘤病例。该病变位于一名70岁女性的乳晕处，类似乳房潜在肿瘤。由于组织病理学显示良性汗孔瘤与毛囊漏斗部有明显连续性，故诊断为大汗腺汗孔瘤。本例汗孔瘤起源于大汗腺。本报告表明，在乳晕后天性病变的临床鉴别诊断中应考虑大汗腺汗孔瘤，提示可能存在潜在的乳房肿瘤。仅部分活检的大汗腺汗孔瘤可能复发。此外，由于大汗腺汗孔瘤可能潜在发展为大汗腺汗孔癌，类似于小汗腺汗孔瘤有时会转变为小汗腺汗孔癌，因此大汗腺汗孔瘤应完整切除。
