Hayreh S S
Department of Ophthalmology and Visual Sciences, University of Iowa College of Medicine, Iowa City, IA 52242-1091, USA.
Prog Retin Eye Res. 2001 Sep;20(5):563-93. doi: 10.1016/s1350-9462(01)00004-0.
Evidence has gradually emerged that there is vascular insufficiency in the optic nerve head (ONH) in both anterior ischemic optic neuropathy (AION) and glaucomatous optic neuropathy (GON); thus both represent ischemic disorders of the ONH. Together these diseases constitute a major cause of blindness or seriously impaired vision in man. Consequently there has recently been great interest in the ONH circulation in health and disease and in how to evaluate it. Many studies of the subject have been published, with conflicting interpretations and claims. The basis of the inconsistent information seems to be confusion on some fundamental issues concerning the ONH circulation itself. The objective of this paper is to differentiate myths and misconceptions from reality about the ONH blood supply; to elucidate the reasons for disagreement on the blood supply of the ONH; and to evaluate the reliability and validity of various methods currently used to measure ONH blood flow.
越来越多的证据表明，前部缺血性视神经病变（AION）和青光眼性视神经病变（GON）均存在视神经乳头（ONH）的血管供血不足；因此，两者均代表ONH的缺血性疾病。这些疾病共同构成了人类失明或视力严重受损的主要原因。因此，近来人们对健康和疾病状态下的ONH循环以及如何评估该循环产生了浓厚兴趣。关于该主题已发表了许多研究，但解释和主张相互矛盾。信息不一致的根本原因似乎是在一些有关ONH循环本身的基本问题上存在混淆。本文的目的是区分关于ONH血液供应的错误观念和误解与现实情况；阐明关于ONH血液供应存在分歧的原因；并评估目前用于测量ONH血流的各种方法的可靠性和有效性。
