Kochansky G E, salzman C, Shader R I, Harmatz J S, Ogeltree A M
Am J Psychiatry. 1975 Aug;132(8):861-3. doi: 10.1176/ajp.132.8.861.
The authors compared the effects of chlordiazepoxide, oxazepam, and placebo on hostility, as an inner motivational or arousal state, in moderately and highly anxious male research volunteers. The data again supported the hypothesis that clordiazepoxide-induced increases in motivational hostility are more frequent and intense than those associated with placebo and oxazepum. The data also suggest that oxazepam may be a more specific "hostility tranquilizer" than other benzodiazepines.
作者比较了氯氮卓、奥沙西泮和安慰剂对中度及高度焦虑的男性研究志愿者作为一种内在动机或唤醒状态的敌意的影响。数据再次支持了以下假设:氯氮卓引起的动机性敌意增加比与安慰剂和奥沙西泮相关的增加更频繁、更强烈。数据还表明,奥沙西泮可能比其他苯二氮䓬类药物更具特异性的“敌意镇静剂”。