[一名甲型血友病合并终末期肝衰竭患者的肝移植]

[Liver transplantation in a patient with hemophilia A and end stage liver failure].

作者信息

Balabaud-Pichon V, Freys G, Faradji A, Wolf P, Pottecher T

机构信息

Département d'anesthésie-réanimation chirurgicale, hôpitaux universitaires de Strasbourg, hôpital civil, 1, place de l'Hôpital, 67000 Strasbourg, France.

出版信息

Ann Fr Anesth Reanim. 2001 Jun;20(6):552-5. doi: 10.1016/s0750-7658(01)00423-3.

DOI:10.1016/s0750-7658(01)00423-3

PMID:11471503

Abstract

We report the case of a 50 year-old man factor VIII deficient haemophiliac and hepatitis C cirrhosis. The patient underwent orthotopic liver transplantation because of episodes of variceal bleeding and encephalopathy. He received factor VIII replacement therapy perioperatively. Factor VIII returned to normal within 24 hours postoperatively and factor VIII replacement was stopped. Liver transplantation can be considered as definitive therapy for haemophilia.

摘要

我们报告一例50岁男性，患有VIII因子缺乏的血友病及丙型肝炎肝硬化。该患者因静脉曲张出血和肝性脑病发作接受了原位肝移植。他在围手术期接受了VIII因子替代治疗。术后24小时内VIII因子恢复正常，VIII因子替代治疗停止。肝移植可被视为血友病的确定性治疗方法。