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因严重牙源性感染而需要或不需要重症监护的患者之间的差异。

Differences between patients with or without the need for intensive care due to severe odontogenic infections.

作者信息

Ylijoki S, Suuronen R, Jousimies-Somer H, Meurman J H, Lindqvist C

机构信息

Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital and Institute of Dentistry, University of Helsinki, Finland.

出版信息

J Oral Maxillofac Surg. 2001 Aug;59(8):867-72; discussion 872-3. doi: 10.1053/joms.2001.25017.

Abstract

PURPOSE

Despite greatly improved dental health in industrialized countries, severe odontogenic infections still occasionally lead to hospitalization. The aim of the present study was to determine whether what symptoms, signs, or laboratory parameters on hospital admission were associated with the need for treatment in the intensive care unit (ICU).

PATIENTS AND METHODS

Over an 18-month period, 100 consecutive patients (59 male, 41 female) were included in the study. Twenty percent of the patients required ICU treatment because of cardiorespiratory problems or severe complications of their infection. Both ICU and non-ICU patients were examined clinically and blood samples were taken and studied in respect to several parameters associated with infection, including C-reactive protein (CRP) levels. The findings were analyzed statistically for differences between the groups.

RESULTS

No particular anamnestic background variable was associated with the need for intensive care. However, a particularly high CRP level on admission was found to be associated with a more severe course of the infection.

CONCLUSIONS

This study showed that determination of CRP levels may be useful in clinical decision-making in patients with severe odontogenic infections.

摘要

目的

尽管工业化国家的口腔健康状况有了很大改善,但严重的牙源性感染仍偶尔导致住院治疗。本研究的目的是确定入院时的哪些症状、体征或实验室参数与重症监护病房(ICU)治疗需求相关。

患者与方法

在18个月的时间里,连续纳入100例患者(59例男性,41例女性)。20%的患者因心肺问题或感染的严重并发症需要ICU治疗。对ICU患者和非ICU患者均进行了临床检查,并采集血样,针对包括C反应蛋白(CRP)水平在内的几个与感染相关的参数进行研究。对研究结果进行统计学分析,以比较两组之间的差异。

结果

没有特定的既往病史背景变量与重症监护需求相关。然而,发现入院时CRP水平特别高与感染的更严重病程相关。

结论

本研究表明,测定CRP水平可能有助于严重牙源性感染患者的临床决策。

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