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老年人牙源性脓肿的预后预测因素

Outcome predictors of odontogenic abscesses in the elderly.

作者信息

Kaercher Daniel, Thelen Philipp, Ruettermann Mike, Li Lei, Hamprecht Axel

机构信息

Department for Oral and Maxillofacial Surgery, Klinikum Oldenburg AöR, Oldenburg, Germany.

Institute of Medical Microbiology and Virology, University of Oldenburg and Klinikum Oldenburg AöR, Oldenburg, Germany.

出版信息

Front Oral Health. 2024 Dec 2;5:1486182. doi: 10.3389/froh.2024.1486182. eCollection 2024.

Abstract

Odontogenic infections have a high prevalence and can lead to severe complications. Due to demographic changes, the number of geriatric patients has increased in recent years. The aim of this study was to analyse odontogenic abscesses in elderly patients and to differentiate them from non-elderly patients regarding clinical presentation, bacterial analysis and therapy. We retrospectively reviewed 1,173 inpatients with odontogenic abscesses from 2014 to 2020. Patients were divided into elderly patients (≥70 years,  = 240) and non-elderly patients (<70 years,  = 933). Demographics, clinical parameters, laboratory values and treatment parameters were analysed. Overall, elderly patients had a longer hospital stay (LOS) (median 4 [range 28] vs. 3 [range 22] days) and more complications (9.6% vs. 7.9%) than non-elderly patients, although these differences were not statistically significant. Peri-/submandibular ( = 0.015), parapharyngeal ( < 0.001) and oral base infections ( = 0.036) were associated with significantly longer LOS in the elderly. Chronic renal failure (CRF) was associated with LOS ( = 0.010) and complications ( = 0.006). In the elderly, c-reactive protein (CRP) correlated significantly with LOS ( < 0.001) and more complications ( = 0.036). This study identifies anatomical spaces and CRF as outcome predictors of odontogenic abscesses in the elderly. In addition, CRP level may serve as a predictor of complicated course in elderly patients.

摘要

牙源性感染发病率高,可导致严重并发症。由于人口结构变化,近年来老年患者数量有所增加。本研究的目的是分析老年患者的牙源性脓肿,并在临床表现、细菌分析和治疗方面将其与非老年患者进行区分。我们回顾性分析了2014年至2020年1173例牙源性脓肿住院患者。患者分为老年患者(≥70岁,n = 240)和非老年患者(<70岁,n = 933)。分析了人口统计学、临床参数、实验室值和治疗参数。总体而言,老年患者的住院时间(LOS)更长(中位数4天[范围2 - 8天] vs. 3天[范围2 - 22天]),并发症更多(9.6% vs. 7.9%),尽管这些差异无统计学意义。颌下/下颌下(p = 0.015)、咽旁(p < 0.001)和口底感染(p = 0.036)与老年患者显著更长的住院时间相关。慢性肾衰竭(CRF)与住院时间(p = 0.010)和并发症(p = 0.006)相关。在老年患者中,C反应蛋白(CRP)与住院时间显著相关(p < 0.001),且并发症更多(p = 0.036)。本研究确定了解剖间隙和CRF是老年患者牙源性脓肿的预后预测因素。此外,CRP水平可作为老年患者病情复杂程度的预测指标。

相似文献

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Outcome predictors of odontogenic abscesses in the elderly.老年人牙源性脓肿的预后预测因素
Front Oral Health. 2024 Dec 2;5:1486182. doi: 10.3389/froh.2024.1486182. eCollection 2024.

本文引用的文献

1
Complications of Severe Odontogenic Infections: A Review.重度牙源性感染的并发症:综述
Biology (Basel). 2022 Dec 8;11(12):1784. doi: 10.3390/biology11121784.
10
Antibiotic sensitivity and resistance of bacteria from odontogenic maxillofacial abscesses.牙源性颌面部脓肿细菌的抗生素敏感性与耐药性
J Korean Assoc Oral Maxillofac Surg. 2019 Dec;45(6):324-331. doi: 10.5125/jkaoms.2019.45.6.324. Epub 2019 Dec 26.

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