Short K R, Nair K S
Endocrinology Research Unit, Mayo Clinic and Foundation, Rochester, Minnesota, USA.
Exerc Sport Sci Rev. 2001 Jul;29(3):118-23. doi: 10.1097/00003677-200107000-00006.
Muscle oxidative function appears to decline with aging, and evidence suggests that this is related to reduced synthesis of mitochondrial and other muscle proteins. Causes for these events may include mtDNA damage or reduced mtDNA copy numbers, reduced oxidative enzyme activities and ATP production, and increased proton leak.
肌肉氧化功能似乎会随着年龄增长而下降，有证据表明这与线粒体及其他肌肉蛋白合成减少有关。这些情况的成因可能包括线粒体DNA损伤或线粒体DNA拷贝数减少、氧化酶活性降低和ATP生成减少，以及质子泄漏增加。
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