Zhang Y, Liu Y
Guang'anmen Hospital, China Academy of Traditional Chinese Medicine, Beijing 100053.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1998 Sep;18(9):534-6.
To test and verify the effects of prostatitis decoction and its capsule on the treatment of chronic prostatitis with blood stasis Syndrome, and its therapeutic mechanism.
Five hundred and sixty-one Patients were treated for 2 months, decoction group 322 cases, and capsule group 239 cases. As control group, 95 cases were treated with Qianliekang tablets. Expressed prostatic secretion(EPS)-pH and Zn content were measured before and after treatment. Observation on hemorheology and microcirculation disturbance with animal experiments were conducted.
The cure rate of Prostatitis decoction and capsule groups was 65.8%, and 54.4% respectively, that of control group was only 17.9%. EPS-pH and Zn were markedly improved after Prostatitis decoction treatment. Experimental work revealed that Prostatitis decoction and its capsule had lowered the whole blood viscosity, thrombocyte adhesiveness rate and dry weight of thrombus in blood stasis rabbit model; and on rats model of microcirculation disturbance caused by adrenalin, the Prostatitis decoction and its capsules had obviously delayed the occurrence of reduction and stopping of blood flow in arterioles.
Prostatitis decoction (capsule) was effective in treating chronic prostatitis.
验证前列腺炎汤及其胶囊治疗慢性前列腺炎血瘀证的疗效及其作用机制。
561例患者治疗2个月，汤剂组322例，胶囊组239例。95例患者服用前列康片作为对照组。治疗前后检测前列腺液（EPS）-pH值和锌含量。通过动物实验观察血液流变学和微循环障碍情况。
前列腺炎汤组和胶囊组的治愈率分别为65.8%和54.4%，对照组仅为17.9%。前列腺炎汤治疗后EPS-pH值和锌含量明显改善。实验研究表明，前列腺炎汤及其胶囊可降低血瘀证家兔模型的全血黏度、血小板黏附率和血栓干重；在肾上腺素所致大鼠微循环障碍模型中，前列腺炎汤及其胶囊可明显延缓微动脉血流减少和停止的发生。
前列腺炎汤（胶囊）治疗慢性前列腺炎有效。
