Laber G, Schütze E
Antimicrob Agents Chemother. 1975 May;7(5):517-21. doi: 10.1128/AAC.7.5.517.
The efficacy of the pleuromutilin derivative 81.723 hfu was tested in chicks and turkey poults by experimentally infecting them with Mycoplasma gallisepticum. The data were treated to obtain the mean effective doses, and these were compared to those obtained with tylosin tartrate. The compounds were administered either by ingluvial catheter or via the drinking water. Therapy was started on the day of inoculation or 7 days thereafter, respectively. The experiments showed that the compound 81.723 hfu was significantly more active in chickens than tylosin tartrate by both methods of administration of drinking water. In turkey poults the pleuromutilin derivative and tylosin tartrate had comparable activity.
通过用鸡毒支原体对雏鸡和小火鸡进行实验性感染，测试了截短侧耳素衍生物81.723 hfu的疗效。对数据进行处理以获得平均有效剂量，并将这些剂量与用酒石酸泰乐菌素获得的剂量进行比较。这些化合物通过嗉囊导管或通过饮用水给药。治疗分别在接种当天或之后7天开始。实验表明，通过饮用水这两种给药方法，化合物81.723 hfu在鸡中的活性明显高于酒石酸泰乐菌素。在小火鸡中，截短侧耳素衍生物和酒石酸泰乐菌素具有相当的活性。
