Weisman Y, Herz A, Yegana Y, Egyed M N, Shlosberg A
Vet Res Commun. 1983 Jun;6(3):189-98. doi: 10.1007/BF02214912.
Healthy turkeys receiving 80 ppm monensin in their feed were injected at 26, 40 and 61 days of age with tiamulin at dosages of 12.5 and 25 mg/kg body weight. The aim of the study was to develop a regime for medicating with tiamulin turkeys receiving monensin in their feed, and which would circumvent the known toxicity created by the simultaneous administration of the two drugs. One injection of 12.5 mg/kg tiamulin up to the age of 61 days or 2 injections of 12.5 mg/kg tiamulin up to 40 days of age caused no mortality or adverse reaction.
在饲料中摄入80 ppm莫能菌素的健康火鸡,在26日龄、40日龄和61日龄时分别注射12.5毫克/千克和25毫克/千克体重的泰妙菌素。该研究的目的是制定一种给在饲料中摄入莫能菌素的火鸡使用泰妙菌素的给药方案,该方案将规避同时使用这两种药物所产生的已知毒性。在61日龄前注射一次12.5毫克/千克的泰妙菌素,或在40日龄前注射两次12.5毫克/千克的泰妙菌素,均未导致死亡或不良反应。