McDaniel C H, Miotto K A
ULCA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, California 90024, USA.
J Psychoactive Drugs. 2001 Apr-Jun;33(2):143-9. doi: 10.1080/02791072.2001.10400479.
There is little medical information available about gamma-hydroxybutyrate (GHB) or gamma-butyrolactone (GBL) dependence or withdrawal. In this study the authors treated and reviewed multiple cases of GHB and GBL withdrawal in high-dose users. Five patients during nine hospitalizations were treated for GHB or GBL withdrawal. The authors describe a spectrum of GHB or GBL withdrawal from mild to severe and discuss medications used for treatment. They conclude that patients with GHB or GBL withdrawal may present with agitated psychosis, delirium, and autonomic instability. In this sample, relapse to GHB or GBL use occurred soon after treatment of withdrawal.
关于γ-羟基丁酸（GHB）或γ-丁内酯（GBL）依赖或戒断的医学信息很少。在本研究中，作者对高剂量使用者中多例GHB和GBL戒断病例进行了治疗和回顾。9次住院期间，有5名患者接受了GHB或GBL戒断治疗。作者描述了从轻度到重度的一系列GHB或GBL戒断情况，并讨论了用于治疗的药物。他们得出结论，GHB或GBL戒断患者可能会出现激越性精神病、谵妄和自主神经不稳定。在这个样本中，戒断治疗后很快就出现了复吸GHB或GBL的情况。
