Daniel L, Zattara-Cannoni H, Lechevallier E, Pellissier J F
Department of Pathology, C-H-U Timone, 13385 Marseille, Cédex 05, France.
J Clin Pathol. 2001 Aug;54(8):637-9. doi: 10.1136/jcp.54.8.637.
This case report describes a 75 year old man who had a renal papillary carcinoma associated with a low grade tumour of the collecting ducts. These tumours showed different immunohistochemical patterns for epithelial membrane antigen, cytokeratin 19, and Ulex europaeus lectin expression. In addition, cytogenetic findings were 47, XY, +7 <7> and 45, XY, -8, add(12)(q-ter)<10> for the papillary renal carcinoma and the low grade tumour of the collecting ducts, respectively. This is the first report where these two types of tumour are associated and cytogenetically distinguished.
本病例报告描述了一名75岁男性,其患有与集合管低级别肿瘤相关的肾乳头状癌。这些肿瘤在上皮膜抗原、细胞角蛋白19和欧洲荆豆凝集素表达方面显示出不同的免疫组化模式。此外,肾乳头状癌和集合管低级别肿瘤的细胞遗传学结果分别为47, XY, +7 <7> 和45, XY, -8, add(12)(q-ter)<10>。这是首次报道这两种类型的肿瘤相关且在细胞遗传学上可区分。