Grampp S, Henk C, Lu Y, Krestan C, Resch H, Kainberger F, Youssefzadeh S, Vorbeck F, Imhof H
Department of Osteology, Universitätsklinik für Radiodiagnostik, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Radiology. 2001 Aug;220(2):400-5. doi: 10.1148/radiology.220.2.r01au05400.
To calculate cutoff levels for quantitative ultrasonography (US) performed to distinguish healthy individuals and those with osteoporosis identified with dual x-ray absorptiometry.
In 1,357 patients (856 females, aged 55.1 years +/- 15.4 [mean +/- SD]; 501 males, aged 50.4 years +/- 15), bone mineral density measurements of the lumbar spine (posteroanterior, L1 through L4) and femoral neck were obtained, and quantitative US was performed to determine the stiffness of the calcaneus. Individuals with a T score less than -2.5 (osteoporotic) at the spine and femur were identified, and upper T-score cutoff values (3 SDs from the mean) in the groups of male and female patients with osteoporosis were identified.
Females with dual x-ray absorptiometric values that were indicative of osteoporosis of the spine had an upper T-score cutoff value of -1.0 (males, -0.2). Females who had femoral osteoporosis showed an upper quantitative US T-score cutoff value of -0.6 (males, 0).
Cutoff values may permit the use of quantitative US to screen for the presence of osteoporosis in the spine and femur. Quantitative US will help to prevent unnecessary dual x-ray absorptiometric and conventional radiographic examinations.
计算用于区分健康个体与经双能X线吸收法鉴定为骨质疏松症患者的定量超声检查（US）的临界值。
对1357例患者（856例女性，年龄55.1岁±15.4[均值±标准差]；501例男性，年龄50.4岁±15岁）进行腰椎（前后位，L1至L4）和股骨颈的骨密度测量，并进行定量超声检查以确定跟骨的硬度。确定脊柱和股骨T值小于-2.5（骨质疏松症）的个体，并确定骨质疏松症男性和女性患者组中的T值上限临界值（距均值3个标准差）。
双能X线吸收法值提示脊柱骨质疏松症的女性T值上限临界值为-1.0（男性为-0.2）。患有股骨骨质疏松症的女性定量超声T值上限临界值为-0.6（男性为0）。
临界值可能允许使用定量超声来筛查脊柱和股骨骨质疏松症的存在。定量超声将有助于避免不必要的双能X线吸收法和传统放射学检查。
