Broekmans W M, Klöpping-Ketelaars W A, Kluft C, van den Berg H, Kok F J, van Poppel G
TNO Nutrition and Food Research, Zeist, The Netherlands.
Eur J Clin Nutr. 2001 Aug;55(8):636-42. doi: 10.1038/sj.ejcn.1601192.
To evaluate the effect of fruit and vegetables consumption on markers of risk for cardiovascular disease.
Randomised, diet controlled, parallel study.
Forty-eight apparently healthy (40--60 y) volunteers with a low usual consumption of fruit and vegetables. Forty-seven of them completed the study.
During 4 weeks 24 volunteers consumed a standardised meal, consisting of 500 g/day fruit and vegetables and 200 ml/day fruit juice ('high' group) and 23 volunteers consumed 100 g/day fruit and vegetables ('low' group) with an energy and fat controlled diet.
Final total cholesterol was 0.2 (95% CI -0.5--0.03) mmol/l lower in the high group than in the low group (P>0.05). Final fibrinogen and systolic blood pressure were 0.1 (-0.1--0.4) g/l and 2.8 (-2.6--8.1) mmHg higher in the high group than in the low group (P>0.05), respectively. Also, other final serum lipid concentrations, diastolic blood pressure and other haemostatic factors did not differ between both groups.
This was a small randomised well-controlled dietary intervention trial of short duration with a considerable contrast in fruit and vegetable consumption. No effects on serum lipids, blood pressure and haemostatic variables were observed.
评估食用水果和蔬菜对心血管疾病风险标志物的影响。
随机、饮食控制、平行研究。
48名表面健康（40 - 60岁）、平时水果和蔬菜摄入量较低的志愿者。其中47人完成了研究。
在4周内，24名志愿者食用标准化餐食，包括每天500克水果和蔬菜以及200毫升果汁（“高”组），23名志愿者食用每天100克水果和蔬菜（“低”组），饮食能量和脂肪含量得到控制。
“高”组的最终总胆固醇比“低”组低0.2（95%可信区间 -0.5 - -0.03）毫摩尔/升（P>0.05）。“高”组的最终纤维蛋白原和收缩压分别比“低”组高0.1（-0.1 - -0.4）克/升和2.8（-2.6 - -8.1）毫米汞柱（P>0.05）。此外，两组之间其他最终血清脂质浓度、舒张压和其他止血因子并无差异。
这是一项小型的、随机、严格控制的短期饮食干预试验，水果和蔬菜摄入量有显著差异。未观察到对血清脂质、血压和止血变量有影响。
