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水果、蔬菜与心血管风险状况:一项饮食控制干预研究。

Fruit and vegetables and cardiovascular risk profile: a diet controlled intervention study.

作者信息

Broekmans W M, Klöpping-Ketelaars W A, Kluft C, van den Berg H, Kok F J, van Poppel G

机构信息

TNO Nutrition and Food Research, Zeist, The Netherlands.

出版信息

Eur J Clin Nutr. 2001 Aug;55(8):636-42. doi: 10.1038/sj.ejcn.1601192.

Abstract

OBJECTIVE

To evaluate the effect of fruit and vegetables consumption on markers of risk for cardiovascular disease.

DESIGN

Randomised, diet controlled, parallel study.

SUBJECTS

Forty-eight apparently healthy (40--60 y) volunteers with a low usual consumption of fruit and vegetables. Forty-seven of them completed the study.

INTERVENTIONS

During 4 weeks 24 volunteers consumed a standardised meal, consisting of 500 g/day fruit and vegetables and 200 ml/day fruit juice ('high' group) and 23 volunteers consumed 100 g/day fruit and vegetables ('low' group) with an energy and fat controlled diet.

RESULTS

Final total cholesterol was 0.2 (95% CI -0.5--0.03) mmol/l lower in the high group than in the low group (P>0.05). Final fibrinogen and systolic blood pressure were 0.1 (-0.1--0.4) g/l and 2.8 (-2.6--8.1) mmHg higher in the high group than in the low group (P>0.05), respectively. Also, other final serum lipid concentrations, diastolic blood pressure and other haemostatic factors did not differ between both groups.

CONCLUSIONS

This was a small randomised well-controlled dietary intervention trial of short duration with a considerable contrast in fruit and vegetable consumption. No effects on serum lipids, blood pressure and haemostatic variables were observed.

摘要

目的

评估食用水果和蔬菜对心血管疾病风险标志物的影响。

设计

随机、饮食控制、平行研究。

受试者

48名表面健康(40 - 60岁)、平时水果和蔬菜摄入量较低的志愿者。其中47人完成了研究。

干预措施

在4周内,24名志愿者食用标准化餐食,包括每天500克水果和蔬菜以及200毫升果汁(“高”组),23名志愿者食用每天100克水果和蔬菜(“低”组),饮食能量和脂肪含量得到控制。

结果

“高”组的最终总胆固醇比“低”组低0.2(95%可信区间 -0.5 - -0.03)毫摩尔/升(P>0.05)。“高”组的最终纤维蛋白原和收缩压分别比“低”组高0.1(-0.1 - -0.4)克/升和2.8(-2.6 - -8.1)毫米汞柱(P>0.05)。此外,两组之间其他最终血清脂质浓度、舒张压和其他止血因子并无差异。

结论

这是一项小型的、随机、严格控制的短期饮食干预试验,水果和蔬菜摄入量有显著差异。未观察到对血清脂质、血压和止血变量有影响。

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