El-Sehrawy Amr Ali Mohamed Abdelgawwad, Jawad Mahmood, Abed Hussein Salim, Bishoyi Ashok Kumar, Alghamdi Salah, Roopashree R, Kundlas Mayank, Nanda Anima, Kariem Muthena, Mustafa Yasser Fakri, Abdulghani Mahfoudh Almusali Mohammed
Department of Internal Medicine, Diabetes, Endocrinology and Metabolism, Mansoura University, Mansoura, Egypt.
Department of Pharmacy, Al-Zahrawi University College, Karbala, Iraq.
BMC Endocr Disord. 2025 Apr 3;25(1):90. doi: 10.1186/s12902-025-01912-5.
Obesity is a major worldwide health problem and is associated with numerous diseases including diabetes, cardiovascular diseases, and some types of cancers. In the current cross-sectional study, we aimed to evaluate the association between a novel dietary obesity prevention score (DOPS) with metabolic parameters including serum lipid profile, glycemic markers, electrolyte status and blood pressure in individuals with obesity.
Three hundred and four individuals with obesity aged 18-65 years old were recruited through convenient sampling; anthropometric and dietary assessments were performed and blood pressure was measured. Biochemical parameters including serum lipids, glycemic markers, some of liver function tests and electrolyte status were measured by standard laboratory methods.
Lower adiposity including lower body mass index (BMI) and fat mass and low systolic and diastolic blood pressures were observed at higher tertiles of versus lower tertiles of DOPS (P < 0.05). Also, lower low density lipoprotein cholesterol (LDL-c) and higher serum albumin concentrations were observed at higher tertiles of DOPS. There was no significant difference between other parameters across DOPS tertiles.
In our study, higher adherence to dietary obesity preventive score reduced obesity risk, blood pressure and serum LDL in individuals with obesity. Future longitudinal and interventional studies are needed to establish causal relationships.
Not applicable.
肥胖是一个全球性的主要健康问题，与多种疾病相关，包括糖尿病、心血管疾病和某些类型的癌症。在当前的横断面研究中，我们旨在评估一种新型饮食肥胖预防评分（DOPS）与肥胖个体的代谢参数之间的关联，这些代谢参数包括血脂谱、血糖标志物、电解质状态和血压。
通过方便抽样招募了304名年龄在18 - 65岁的肥胖个体；进行了人体测量和饮食评估，并测量了血压。通过标准实验室方法测量生化参数，包括血脂、血糖标志物、一些肝功能测试和电解质状态。
与DOPS较低三分位数相比，在较高三分位数时观察到较低的肥胖程度，包括较低的体重指数（BMI）和脂肪量以及较低的收缩压和舒张压（P < 0.05）。此外，在DOPS较高三分位数时观察到较低的低密度脂蛋白胆固醇（LDL - c）和较高的血清白蛋白浓度。在DOPS三分位数之间的其他参数没有显著差异。
在我们的研究中，较高的饮食肥胖预防评分依从性降低了肥胖个体的肥胖风险、血压和血清LDL。需要未来的纵向和干预性研究来建立因果关系。
不适用。
