Helms G, Piringer A
MR Research Center, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Magn Reson Med. 2001 Aug;46(2):395-400. doi: 10.1002/mrm.1203.
A postprocessing method to restore motion-related signal loss and line-shape deterioration in single-volume proton MR spectroscopy (MRS) is presented. Each acquisition is corrected by its phase offset and frequency shift, extracted from the residual water signal prior to averaging. Requirements are good gradient selection and selective suppression of CSF in residual water. Stimulated echo acquisition mode (STEAM) spectra (TE = 30 ms) were analyzed using the LCModel program to study gains in metabolite signal and spectral quality in five brain regions. Increases of total N-acetyl-aspartate concentrations of up to 5% were observed. The method may be beneficial for clinical examinations of less compliant subjects and for dynamic spectroscopy.
本文提出了一种后处理方法，用于恢复单容积质子磁共振波谱（MRS）中与运动相关的信号损失和线形恶化。每次采集都通过其相位偏移和频率偏移进行校正，这些偏移是在平均之前从残留水信号中提取的。要求是良好的梯度选择以及对残留水中脑脊液的选择性抑制。使用LCModel程序分析刺激回波采集模式（STEAM）光谱（TE = 30 ms），以研究五个脑区代谢物信号和光谱质量的增益。观察到总N-乙酰天门冬氨酸浓度增加高达5%。该方法可能对不太配合的受试者的临床检查以及动态波谱分析有益。
