Aranyosi J, Péterffy A, Zatik J, Kerenyi D T, Lampé L, Borsos A
Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Szülészeti és Nógyógyászati Klinika.
Orv Hetil. 2001 Jul 1;142(26):1397-402.
The incidence of heart disease in pregnancy has been gradually falling during the last three decades. Cardiopathy still remains a prominent cause of maternal and fetal morbidity and mortality. Most patients know about their heart disease long before conception, even though the potential risk factors of deteriorating cardiac function during pregnancy are generally not emphasized. These women when pregnant may develop heart failure due to the increased cardiorespiratory requirements. When medical therapy proves insufficient heart surgery becomes mandatory to save the patient's life. The pregnant state is not optimal for cardiac surgery as the principle interest of the mother and the fetus is different. We report on two pregnant patients who underwent unavoidable heart surgery with cardiopulmonary bypass and review the literature regarding the optimal management of open-heart operation in pregnancy aiming to decrease the feto-maternal mortality. The successful outcome of the cardiac surgery on pregnant women is determined by the severity of the preexisting disease, the surgical techniques, and the circumstances of the cardiopulmonary bypass. The best possible results can be achieved by providing preconceptional counseling for the cardiopathic patients regarding the relation between the preexisting risk factors and the adverse maternal and neonatal outcome. When heart surgery is mandatory in pregnancy the careful technical precautions and the continuous cardiotocography help to minimize fetal complications during the cardiopulmonary bypass (CPB).
在过去三十年中,妊娠期间心脏病的发病率一直在逐渐下降。心脏病仍然是孕产妇和胎儿发病及死亡的一个主要原因。大多数患者在受孕前很久就知道自己患有心脏病,尽管妊娠期间心脏功能恶化的潜在风险因素通常未得到强调。这些女性怀孕时,可能会由于心肺需求增加而发生心力衰竭。当药物治疗证明不足时,心脏手术就成为挽救患者生命的必要手段。由于母亲和胎儿的主要利益不同,妊娠状态并非心脏手术的最佳时机。我们报告了两名接受了不可避免的体外循环心脏手术的孕妇,并回顾了关于妊娠期间心脏直视手术最佳管理的文献,旨在降低母婴死亡率。孕妇心脏手术的成功结果取决于原有疾病的严重程度、手术技术以及体外循环的情况。通过为心脏病患者提供关于原有风险因素与不良母婴结局之间关系的孕前咨询,可以取得最好的结果。当妊娠期间必须进行心脏手术时,仔细的技术预防措施和持续的胎心监护有助于将体外循环期间的胎儿并发症降至最低。