Kobayashi K, Fujitani K, Tsujinaka T, Kikkawa N
Dept. of Surgery, Kinki Central Hospital.
Gan To Kagaku Ryoho. 2001 Jul;28(7):961-4.
Clinical results after non-curative resection of highly advanced esophageal cancer are extremely poor. We administered concurrent chemoradiation therapy (CRT) as a multidisciplinary therapy in cases of highly advanced esophageal cancer for which non-curative resection is expected. The efficacy rate of the therapy was 59.4%, and the 3-year-survival rate 10.2%. A life-prolonging effect (the 3-year survival being 17.9%) was observed in the effective cases. Our future aim is to establish a safer, more reliable and cost-effective therapy by estimating the degree of efficacy before administration of CRT and then selecting cases suitable for CRT.
高度进展期食管癌非根治性切除术后的临床结果极差。对于预期无法进行根治性切除的高度进展期食管癌患者，我们采用同步放化疗（CRT）作为多学科治疗方法。该治疗方法的有效率为59.4%，3年生存率为10.2%。在有效病例中观察到了延长生命的效果（3年生存率为17.9%）。我们未来的目标是通过在进行CRT之前评估疗效程度，然后选择适合CRT的病例，建立一种更安全、更可靠且性价比更高的治疗方法。
