瑞士肠外营养前瞻性调查：一项为期三年的全国性调查。

Prospective survey of parenteral nutrition in Switzerland: a three-year nation-wide survey.

作者信息

Pichard C, Mühlebach S, Maisonneuve N, Sierro C

机构信息

Clinical Nutrition, Geneva University Hospital.

出版信息

Clin Nutr. 2001 Aug;20(4):345-50. doi: 10.1054/clnu.2001.0428.

DOI:10.1054/clnu.2001.0428

PMID:11478833

Abstract

BACKGROUND AND AIMS

The goals of this national survey were to determine the current PN practices and admixture formulations used in Switzerland.

METHODS

During three years, an annual questionnaire was sent to all heads of Swiss hospital pharmacies.

RESULTS

92% of Swiss hospitals with a full-time pharmacist participated. Different PN systems were commonly used for adult patients: 2 commercial formulas in 2 or 3 compartments bags, 2 commercial formulas with/without lipid, 3 formulas compounded by the hospital pharmacy. For hospitalized adults, 83% of PN bags were administered as commercial multicompartment bags. The compounding of individualized PN admixtures takes place primarily in pharmacies of medium to large size hospitals. For pediatric PN, hospital compounding is routine because of individualized PN compositions and absence of commercially available standardized admixtures. Long-term home-PN was mostly delivered by hospital pharmacies (57%) or by private nutrition support home delivery services (37%). Most PN formula compositions complied with European guidelines and represented 2.6+/-2.0% of the hospital drug budget. Multi-disciplinary nutritional support teams were present in 52% of hospitals.

CONCLUSION

In Switzerland, most PN for hospitalized adults were administered as commercial multi-compartment bags. The compounding of individualized PN admixtures were still important for pediatric patients and long-term home-PN.

摘要

背景与目的

这项全国性调查的目的是确定瑞士目前使用的肠外营养（PN）实践和混合制剂配方。

方法

在三年时间里，每年向瑞士所有医院药房负责人发送一份调查问卷。

结果

92%配备全职药剂师的瑞士医院参与了调查。不同的PN系统常用于成年患者：2种双腔或三腔袋的商业配方、2种含/不含脂肪乳的商业配方、3种由医院药房配制的配方。对于住院成年患者，83%的PN袋以商业多腔袋的形式给药。个体化PN混合制剂的配制主要在大中型医院的药房进行。对于儿科PN，由于PN成分个体化且缺乏市售标准化混合制剂，医院配制是常规操作。长期家庭PN大多由医院药房提供（57%）或由私人营养支持家庭配送服务提供（37%）。大多数PN配方组成符合欧洲指南，占医院药品预算的2.6±2.0%。52%的医院设有多学科营养支持团队。