Ayers Phil, Berger Mette M, Berlana David, Cogle Sarah V, De Cloet Joeri, Gray Brenda, Klek Stanislaw, Kumpf Vanessa J, Monczka Jessica, Ybarra Joe, Zeraschi Sarah, Wischmeyer Paul E
Clinical Pharmacy Services, Department of Pharmacy, Baptist Medical Center, Jackson, MS.
University of Mississippi School of Pharmacy, Jackson, MS, USA.
Am J Health Syst Pharm. 2024 Jun 13;81(Supplement_3):S75-S88. doi: 10.1093/ajhp/zxae078.
The International Safety and Quality of Parenteral Nutrition (PN) Summit consisted of presentations, discussions, and formulation of consensus statements. The purpose here is to briefly summarize the summit and to present the consensus statements.
There was a high degree of consensus, with all statements approved by all authors/summit experts. These consensus statements should be regarded not as formal guidelines but rather as best-practice guidance intended to complement national and international nutrition society evidence-based guidelines and position statements. This article also summarizes key discussion topics from the summit, encompassing up-to-date knowledge and practical guidance concerning PN safety and quality in various countries and clinical settings, focusing on adult patients. Clear geographical differences exist between practices in Europe and the United States, and different approaches to improve the safety, quality, and cost-effectiveness of PN vary, particularly with regard to the delivery systems used. Discussion between experts allowed for an exchange of practical experience in optimizing PN use processes, opportunities for standardization, use of electronic systems, potential improvements in PN formulations, better management during PN component shortages, and practical guidance to address patients' needs, particularly during long-term/home PN.
The consensus statements are the collective opinion of the panel members and form best-practice guidance. The authors intend that this guidance may help to improve the safety and quality of PN in a variety of settings by bridging the gap between published guideline recommendations and common practical issues.
肠外营养(PN)国际安全与质量峰会包括演讲、讨论以及共识声明的制定。本文旨在简要总结该峰会并展示共识声明。
达成了高度共识,所有声明均得到所有作者/峰会专家的认可。这些共识声明不应被视为正式指南,而应被视为最佳实践指导,旨在补充国家和国际营养学会基于证据的指南及立场声明。本文还总结了峰会的关键讨论主题,涵盖各国及临床环境中有关PN安全与质量的最新知识及实践指导,重点针对成年患者。欧洲和美国的实践存在明显的地域差异,且在改善PN安全性、质量及成本效益方面的不同方法各异,尤其是在使用的输送系统方面。专家之间的讨论促进了优化PN使用流程的实践经验交流、标准化机会、电子系统的使用、PN配方的潜在改进、PN成分短缺期间的更好管理以及满足患者需求的实践指导,特别是在长期/家庭PN期间。
共识声明是小组成员的集体意见,形成了最佳实践指导。作者希望该指导能够通过弥合已发表的指南建议与常见实际问题之间的差距,在各种环境中帮助提高PN的安全性和质量。