Van Heyningen S, King C A
Biochem J. 1975 Jan;146(1):269-71. doi: 10.1042/bj1460269.
Intact cholera toxin and its purified subunit A both activate the adenylate cyclase of pigeon erythrocyte membranes, but subunit B does not. The activation by subunit A is unaffected by treatments that inhibit whole toxin by interfering with the binding of subunit B to cell membranes.
完整的霍乱毒素及其纯化的A亚基均可激活鸽红细胞膜的腺苷酸环化酶,但B亚基则不能。A亚基的激活不受通过干扰B亚基与细胞膜结合来抑制全毒素的处理的影响。