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人绒毛膜促性腺激素对新生儿和成年人不同组中血液游离脂肪酸、葡萄糖以及皮下脂肪组织游离脂肪酸释放的影响。

Effect of human chorionic gonadotropin on blood free fatty acids, glucose and on the release of free fatty acids from subcutaneous adipose tissue in various groups of newborn and adults.

作者信息

Melichar V, Rázová M, Dyková H, Vízek K

出版信息

Biol Neonate. 1975;27(1-2):80-7. doi: 10.1159/000240762.

Abstract

After administration of human chorionic gonadotropin (HCG; 500 IU/kg intramuscularly), the blood concentration of free fatty acids increases within 30 min in 1-day-old full-term, premature and small-for-data newborns. This effect does not appear in 1-day-old newborns of diabetic mothers with insulin-dependent diabetes, in 7-day-old newborns nor in adults. Glucose concentration rises in all groups of newborns, and no effect is observed in adults. In the in vitro study, HCG increases lipolysis in newborns' adipose tissue. This effect was not observed in adults.

摘要

给予人绒毛膜促性腺激素(HCG;500 IU/kg肌肉注射)后,出生1天的足月、早产和小于胎龄新生儿在30分钟内游离脂肪酸的血浓度会升高。这种效应在患有胰岛素依赖型糖尿病的糖尿病母亲的1日龄新生儿、7日龄新生儿以及成年人中均未出现。所有新生儿组的葡萄糖浓度均升高,而在成年人中未观察到影响。在体外研究中,HCG可增加新生儿脂肪组织的脂肪分解。在成年人中未观察到这种效应。

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