A novel mutation in islet amyloid polypeptide (IAPP) gene promoter is associated with Type II diabetes mellitus.

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作者信息

Novials A, Rojas I, Casamitjana R, Usac E F, Gomis R

出版信息

Diabetologia. 2001 Aug;44(8):1064-5. doi: 10.1007/s001250100599.

DOI:10.1007/s001250100599

PMID:11484088

Abstract

摘要

相似文献

A novel mutation in islet amyloid polypeptide (IAPP) gene promoter is associated with Type II diabetes mellitus.

Diabetologia. 2001 Aug;44(8):1064-5. doi: 10.1007/s001250100599.

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Mutation at position -132 in the islet amyloid polypeptide ( IAPP) gene promoter enhances basal transcriptional activity through a new CRE-like binding site.

Diabetologia. 2004 Jul;47(7):1167-1174. doi: 10.1007/s00125-004-1439-y. Epub 2004 Jul 9.

Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes?

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-To: Poa NR, Cooper GJS, Edgar PF: Amylin gene promoter mutations predispose to Type 2 diabetes in New Zealand Maori. Diabetologia 46: 574-578.

Diabetologia. 2003 Dec;46(12):1708-9. doi: 10.1007/s00125-003-1243-0. Epub 2003 Nov 5.

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