Miethe G, Surmann J P
Institute of Pharmacy, Humboldt University Berlin, Germany.
Pharmazie. 2001 Jul;56(7):542-7.
A method was developed to quantify the sulphur formed in decomposed sodium thiosulphate injection solutions. Elemental sulphur was extracted with cyclohexane (LLE) and analysed by RP-HPLC. A linear calibration curve with a detection limit of 24 micrograms/ml was obtained. Different amounts of sulphur were detected in extemporaneous and commercial solutions.
