Haaxma R, Kuypers H G
Brain. 1975 Jun;98(2):239-60. doi: 10.1093/brain/98.2.239.
An attempt has been made to elucidate in the rhesus monkey the role of intrahemispheric cortico-cortical connexions in visual guidance of relatively independent hand and finger movements which are governed mainly from the precentral motor cortex. These movements were tested by requiring the animals to retrieve with their fingers small food pellets from a special test board in which the pellets were easily visible but were more difficult to palpate. Unilateral occipital lobectomy combined with a commissurotomy impaired the performance of the contralateral hand. The same was true for the parietal leucotomy of Myers et al. (1962) which transects the bulk of the intrahemispheric occipitofrontal cortical fibres. Tests of the visual discrimination of the leucotomized hemispheric showed that the motor impairment after this leucotomy did not represent a visual defect. In control animals no impairment was found after ablation of the cortex on the surface of the postcentral gyrus and the superior parietal lobule. A mild impairment occurred, however, when the lesion either involved also the inferior parietal lobule or was accompanied by a white matter infarct deep under the postcentral gyrus. The findings make it likely that the intrahemispheric cortical fibres to the frontal lobe play a role in visual guidance of relatively independent hand and finger movements. This conclusion is also supported by some preliminary findings after frontal lobe lesions, but further experiments are necessary to establish it firmly.
人们试图在恒河猴身上阐明半球内皮质 - 皮质连接在相对独立的手部和手指运动的视觉引导中的作用，这些运动主要受中央前运动皮层控制。通过要求动物用手指从一个特殊的测试板上取回小食物颗粒来测试这些运动，在这个测试板上，颗粒很容易看到，但很难触摸到。单侧枕叶切除术联合连合切开术损害了对侧手的表现。迈尔斯等人（1962年）进行的顶叶白质切断术切断了大部分半球内枕额皮质纤维，情况也是如此。对白质切断术半球的视觉辨别测试表明，这种白质切断术后的运动障碍并不代表视觉缺陷。在对照动物中，中央后回表面和顶上小叶的皮质切除后未发现损伤。然而，当病变也累及顶下小叶或伴有中央后回深部白质梗死时，会出现轻度损伤。这些发现表明，半球内到额叶的皮质纤维在相对独立的手部和手指运动的视觉引导中起作用。额叶病变后的一些初步发现也支持这一结论，但需要进一步的实验来牢固确立这一结论。
