Matthys Koen, Smits Marion, Van der Geest Jos N, Van der Lugt Aad, Seurinck Ruth, Stam Henk J, Selles Ruud W
Department of Rehabilitation Medicine, Erasmus Medical Center Rotterdam, The Netherlands.
Arch Phys Med Rehabil. 2009 Apr;90(4):675-81. doi: 10.1016/j.apmr.2008.09.571.
To identify neural networks associated with the use of a mirror to superimpose movement of 1 hand on top of a nonmoving contralateral hand (often referred to as mirror therapy or mirror-induced visual illusion).
A functional magnetic resonance imaging (fMRI) study of mirror-induced visual illusion of hand movements using a blocked design in a 1.5T magnetic resonance imaging scanner. Neural activation was compared in a no-mirror experiment and a mirror experiment. Both experiments consisted of blocks of finger tapping of the right hand versus rest. In the mirror experiment, movement of the left hand was simulated by mirror reflection of right hand movement.
University medical center.
Eighteen healthy subjects.
Not applicable.
Differences in fMRI activation between the 2 experiments.
In the mirror experiment, we found supplementary activation compared with the no-mirror experiment in 2 visual areas: the right superior temporal gyrus (STG) and the right superior occipital gyrus.
In this study, we found 2 areas uniquely associated with the mirror-induced visual illusion of hand movements: the right STG and the right superior occipital gyrus. The STG is a higher-order visual region involved in the analysis of biological stimuli and is activated by observation of biological motion. The right superior occipital gyrus is located in the secondary visual cortex within the dorsal visual stream. In the literature, the STG has been linked with the mirror neuron system. However, we did not find activation within the frontoparietal mirror neuron system to support further a link with the mirror neuron system. Future studies are needed to explore the mechanism of mirror induced visual illusions in patient populations in more detail.
识别与使用镜子将一只手的动作叠加在静止的对侧手上（通常称为镜像疗法或镜像诱发视觉错觉）相关的神经网络。
在1.5T磁共振成像扫描仪中采用组块设计，对镜像诱发的手部动作视觉错觉进行功能磁共振成像（fMRI）研究。在无镜像实验和镜像实验中比较神经激活情况。两个实验均包括右手手指敲击与休息的组块。在镜像实验中，通过右手动作的镜像反射模拟左手动作。
大学医学中心。
18名健康受试者。
不适用。
两个实验之间fMRI激活的差异。
在镜像实验中，与无镜像实验相比，我们在两个视觉区域发现了额外激活：右侧颞上回（STG）和右侧枕上回。
在本研究中，我们发现了两个与镜像诱发的手部动作视觉错觉独特相关的区域：右侧STG和右侧枕上回。STG是一个参与生物刺激分析的高级视觉区域，通过观察生物运动而被激活。右侧枕上回位于背侧视觉通路的二级视觉皮层内。在文献中，STG与镜像神经元系统有关。然而，我们未在前顶叶镜像神经元系统中发现激活，以进一步支持与镜像神经元系统的联系。未来需要开展更多研究，更详细地探索患者群体中镜像诱发视觉错觉的机制。
