Danuser H, Hochreiter W W, Ackermann D K, Studer U E
Department of Urology, Inselspital, University of Bern, Bern, Switzerland.
J Urol. 2001 Sep;166(3):902-9.
We evaluated the influence of stent size in 2 consecutive series of unselected patients in whom primary ureteropelvic junction obstruction was managed by antegrade endopyelotomy and stenting with a 14 or 27Fr stent at the level of the incision.
Antegrade endopyelotomy was performed in 132 patients with primary ureteropelvic junction obstruction. The endopyelotomy was stented for 6 weeks. In 77 patients (group 1) a 14/8.2Fr percutaneous endopyelotomy (Smith) catheter was used. In 55 patients (group 2) a modified 14/8.2Fr Smith catheter was over pulled with a 27Fr wound drain. The wound drain was removed after 2 to 3 weeks and the standard 14/8.2Fr stent remained in place for another 3 to 4 weeks. Success at 6 to 8 weeks, and 6 and 24 months postoperatively was based on clinical evaluation, and excretory urography and/or diuretic renography. Thereafter clinical and ultrasound followup was performed every 2 to 3 years.
Preoperatively data on the risk factors of large pyelocaliceal volume and impaired renal function were similar in the 2 groups. The overall success rate was 70% in group 1 at a median followup of 67 months (range 2 to 118) and 94% in group 2 at a median followup of 23 months (range 2 to 52). The early success rate after 6 to 8 weeks in groups 1 and 2 was 83% and 94%, respectively. The long-term success rate after 2 years was 71% and 93%, respectively. Perioperatively and postoperatively the incidence of complications was 16% in group 1 and 24% in group 2. When group 2 complications due to a lack of experience with the new stent were excluded from analysis, the remaining 15% complication rate was comparable to that in group 1. Mean pyelocaliceal volume decreased significantly in each group and remained stable. Split renal function did not change preoperatively to postoperatively with no significant difference in the 2 groups.
Stenting an antegrade endopyelotomy with a modified 27Fr instead of a 14Fr catheter seems to increase the early and, even more impressively, the long-term success rate to a level similar to that of open pyeloplasty.
我们在连续两组未经挑选的患者中评估了支架尺寸的影响,这些患者的原发性肾盂输尿管连接部梗阻通过顺行肾盂内切开术并在切口处使用14或27Fr支架进行治疗。
对132例原发性肾盂输尿管连接部梗阻患者进行顺行肾盂内切开术。肾盂内切开术后置入支架6周。77例患者(第1组)使用14/8.2Fr经皮肾盂内切开术(史密斯)导管。55例患者(第2组)使用改良的14/8.2Fr史密斯导管,并套入一根27Fr伤口引流管。2至3周后拔除伤口引流管,标准的14/8.2Fr支架再留置3至4周。术后6至8周以及术后6个月和24个月的成功率基于临床评估、排泄性尿路造影和/或利尿肾图。此后每2至3年进行临床和超声随访。
两组术前肾盂肾盏容积大及肾功能受损等危险因素的数据相似。第1组在中位随访67个月(范围2至118个月)时总体成功率为70%,第2组在中位随访23个月(范围2至52个月)时总体成功率为94%。第1组和第2组术后6至8周的早期成功率分别为83%和94%。2年后的长期成功率分别为71%和93%。第1组围手术期和术后并发症发生率为16%,第2组为24%。当将第2组因对新支架缺乏经验导致的并发症排除在分析之外时,其余15%的并发症发生率与第1组相当。每组肾盂肾盏平均容积均显著减小且保持稳定。分肾功能术前至术后无变化,两组间无显著差异。
用改良的27Fr导管而非14Fr导管对顺行肾盂内切开术进行支架置入似乎可提高早期成功率,更显著的是提高长期成功率,使其达到与开放性肾盂成形术相似的水平。