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470例连续开放性肾盂成形术中外置肾盂输尿管支架与标准支架的疗效分析及成本比较

Outcome analysis and cost comparison between externalized pyeloureteral and standard stents in 470 consecutive open pyeloplasties.

作者信息

Braga Luis H P, Lorenzo Armando J, Farhat Walid A, Bägli Darius J, Khoury Antoine E, Pippi Salle Joao L

机构信息

Division of Urology, Hospital for Sick Children and University of Toronto, Toronto, Ontario Canada.

出版信息

J Urol. 2008 Oct;180(4 Suppl):1693-8; discussion1698-9. doi: 10.1016/j.juro.2008.05.084. Epub 2008 Aug 16.

Abstract

PURPOSE

Despite the widespread use of ureteral stents for pyeloplasty by pediatric urologists there is ongoing controversy regarding the most advantageous type of transanastomotic drainage. We compared patients who underwent placement of an externalized pyeloureteral Salle intraoperative pyeloplasty stent (Cook Urological, Spencer, Indiana) to those who had a standard Double-J ureteral stent placed to assess the benefits, drawbacks and costs of each modality during open pyeloplasty.

MATERIALS AND METHODS

Our study sample comprised 470 age matched children who underwent primary open pyeloplasty in an 11-year period. A total of 242 patients (51.5%) underwent Double-J ureteral stent insertion and 228 (48.5%) underwent placement of a Salle intraoperative pyeloplasty stent at surgery. Operative time, hospital stay, overall complication and success rates, type of complications and hospital costs were compared between the 2 groups.

RESULTS

Median age was 18 months and median followup was 39 months. Mean hospital stay was 3.0 and 3.1 days in children with a Double-J ureteral and a Salle intraoperative pyeloplasty stent, respectively (p = 0.7). The overall complication rate was 9.9% (24 of 242 patients) for the Double-J ureteral stent vs 8.3% (19 of 228) for the Salle intraoperative pyeloplasty stent (p = 0.6). Complications in patients with a Double-J ureteral stent consisted of urinoma in 3, return visits due to bladder spasms in 7 or catheter obstruction in 6 and readmission due to pyelonephritis in 5. Complications in children with a Salle intraoperative pyeloplasty stent involved urinoma in 1, prolonged drainage through the Penrose drain in 5 and readmission due to pyelonephritis in 1. Recurrent ureteropelvic junction obstruction developed in 12 cases per group. The success rate was 95.0% (230 of 242 cases) and 94.7% (216 of 228) for the Double-J ureteral and the Salle intraoperative pyeloplasty stent, respectively (p = 0.2). Hospital charges, including the surgical procedure, postoperative hospitalization and cystoscopy or a clinical visit for catheter removal, in patients with a Double-J ureteral and a Salle intraoperative pyeloplasty stent were $9,825 and $9,260, respectively.

CONCLUSIONS

The 2 ureteral stents are equivalent in regard to overall complication and success rates after pyeloplasty. However, Salle intraoperative pyeloplasty stent insertion was associated with a Canadian $565 cost decrease per patient and most importantly the preclusion of a second general anesthesia for catheter removal.

摘要

目的

尽管小儿泌尿外科医生广泛使用输尿管支架进行肾盂成形术,但对于最有利的经吻合口引流类型仍存在争议。我们将接受外置肾盂输尿管萨勒术中肾盂成形术支架(库克泌尿外科公司,印第安纳州斯宾塞)置入的患者与接受标准双J输尿管支架置入的患者进行比较,以评估开放肾盂成形术期间每种方式的益处、缺点和成本。

材料与方法

我们的研究样本包括470名年龄匹配的儿童,他们在11年期间接受了初次开放肾盂成形术。共有242例患者(51.5%)在手术中插入双J输尿管支架,228例(48.5%)在手术中置入萨勒术中肾盂成形术支架。比较两组的手术时间、住院时间、总体并发症和成功率、并发症类型及住院费用。

结果

中位年龄为18个月,中位随访时间为39个月。双J输尿管支架组和萨勒术中肾盂成形术支架组患儿的平均住院时间分别为3.0天和3.1天(p = 0.7)。双J输尿管支架组的总体并发症发生率为9.9%(242例患者中的24例),而萨勒术中肾盂成形术支架组为8.3%(228例中的19例)(p = 0.6)。双J输尿管支架组患者的并发症包括尿瘤3例、因膀胱痉挛复诊7例、导管阻塞6例以及肾盂肾炎再次入院5例。萨勒术中肾盂成形术支架组患儿的并发症包括尿瘤1例、经彭罗斯引流管引流时间延长5例以及肾盂肾炎再次入院1例。每组均有12例发生复发性输尿管肾盂连接部梗阻。双J输尿管支架组和萨勒术中肾盂成形术支架组的成功率分别为95.0%(242例中的230例)和94.7%(228例中的216例)(p = 0.2)。双J输尿管支架组和萨勒术中肾盂成形术支架组患者的住院费用,包括手术、术后住院以及膀胱镜检查或拔除导管的临床就诊费用,分别为9825美元和9260美元。

结论

两种输尿管支架在肾盂成形术后的总体并发症和成功率方面相当。然而,置入萨勒术中肾盂成形术支架每位患者的费用降低了565加元,最重要的是避免了拔除导管时的再次全身麻醉。

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