Boura P, Kountouras J, Lygidakis N J
Department of Medicine, Second Medical Clinic, Aristotelian University of Thessaloniki, Thessaloniki, Greece.
Hepatogastroenterology. 2001 Jul-Aug;48(40):1040-4.
Recent advances in understanding fundamental mechanisms of regulation of the immune response are throwing light into mechanisms of tumor growth. The understanding of the immunological aspects of tumor expansion is leading to the development of new strategies to stimulate the immune system to mount more effective responses to tumors. This progress as well as some promising results in clinical trials is generating considerable optimism. The goal of this review is to present recent advances concerning tumor immunology, identify some of the pitfalls and problems that still exist and present new areas of immunotherapy that look promising.
在理解免疫反应调控基本机制方面的最新进展,正为肿瘤生长机制带来新的启示。对肿瘤扩展免疫方面的认识,正促使新策略的开发,以刺激免疫系统对肿瘤发起更有效的反应。这一进展以及临床试验中的一些 promising results 正带来相当大的乐观情绪。本综述的目的是介绍肿瘤免疫学的最新进展,识别仍然存在的一些陷阱和问题,并介绍看起来有前景的免疫治疗新领域。 (注:“promising results”直译为“有前景的结果”,这里意译为“令人鼓舞的结果”更符合语境)