Kiss J, Koritsánszky S
Cell Tissue Res. 1975 Jun 9;159(2):267-77. doi: 10.1007/BF00219161.
The protein-synthesizing activity of oligodendroglial cells in the rat hippocampus as well as the migration of the newly synthesized proteins within these cells were examined by means of light and microscopic autoradiography when injecting 3H-leucine into the lateral ventricle. The autoradiographs of oligodendroglial cells were compared with the autoradiographs on hippocampal pyramidal cells of the same area. According to the quantitative evaluation of the autoradiographs the protein-synthesizing activity of the oligodendrocytes equals or may even exceed that of the pyramidal cells. In oligodendroglial cells most of the newly synthesized proteins migrate very rapidly from the rough-surfaced endoplasmic reticulum into the cisternae of the Golgi apparatus and disappear continuously. The proteins disappear from the Golgi apparatus simultaneously with the decrease in the radioactive concentration of the perikaryon.
向大鼠侧脑室内注射³H-亮氨酸后，利用光学显微镜和显微放射自显影技术，检测大鼠海马中少突胶质细胞的蛋白质合成活性以及这些细胞内新合成蛋白质的迁移情况。将少突胶质细胞的放射自显影片与同一区域海马锥体细胞的放射自显影片进行比较。根据放射自显影片的定量评估，少突胶质细胞的蛋白质合成活性等于甚至可能超过锥体细胞。在少突胶质细胞中，大多数新合成的蛋白质从糙面内质网迅速迁移到高尔基体的潴泡中，并持续消失。蛋白质从高尔基体中消失的同时，胞核放射性浓度降低。
