Nishida Y, Akaoka I, Nishizawa T, Yoshimura T
Clin Chim Acta. 1975 Jul 9;62(1):103-6. doi: 10.1016/0009-8981(75)90285-5.
Significant elevations of plasma triglyceride and free fatty acids levels were shown in 107 gouty patients, but no significant difference was found in plasma cholesterol and phospholipid levels as compared with control subjects. A positive correlation was found between plasma triglyceride and free fatty acids levels (r = 0.249, P less than 0.05) in gouty patients. The heavy drinkers with gout (15.9% of the patients) had significantly higher plasma triglyceride, free fatty acids and gamma-glutamyltranspeptidase levels than the moderate or non-drinking gouty subjects. These results suggested that excessive intake of alcohol may play an important role in inducing hyperlipidaemia in gout.
107例痛风患者血浆甘油三酯和游离脂肪酸水平显著升高,但与对照组相比,血浆胆固醇和磷脂水平无显著差异。痛风患者血浆甘油三酯和游离脂肪酸水平呈正相关(r = 0.249,P<0.05)。痛风的重度饮酒者(占患者的15.9%)血浆甘油三酯、游离脂肪酸和γ-谷氨酰转肽酶水平显著高于中度饮酒或不饮酒的痛风患者。这些结果表明,过量饮酒可能在痛风患者高脂血症的发生中起重要作用。